Data Access to PRECISE SG100K

Near-Term

As the PRECISE-SG100K resource is being generated and curated, we are facilitating early data access for:

Investigator Initiated Studies. Funded by an NMRC OF-LCG grant that brought together four longitudinal cohorts in Singapore, the SG100K cohort is an Investigator-Initiated Study focused on determinants and prediction of cardiovascular disease and diabetes in Asian populations. To fulfil the grant award obligations and deliverables, the researchers from SG100K Institutions who have created the SG100K cohort have an initial period of priority to pursue research on these chronic conditions.
Call for Proposals. To enable research across a wide range of use cases beyond cardiovascular disease and diabetes, early access to the intermediate data release of 50,000 participants by Singapore public academic and clinical researchers was enabled through an open Call for Proposals (application closed in January 2024). The PRECISE-SG100K Scientific Committee selected 36 projects, comprising 8 Flagship Projects and 28 Driver Projects.
Strategic Industry Partnerships. Coordinated by PRECISE Business Development Team, strategic industry collaborations are being established to strengthen precision medicine research capacity and capability in Singapore.

Mid-Term

We anticipate that the PRECISE-SG100K dataset will become broadly open to Singapore public academic and clinical researchers directly through the TRUST platform from 2027.

Access by overseas researchers or industry partners will remain contingent on the application being led by a Singapore research team.

All applications that request use of linked electronic health records will be subject to additional review by TRUST DAC.

Early Access Mechanisms (2024 – 2026)

Access by public researchers in Singapore: PRECISE-SG100K will launch a 2^nd Call for Proposals in first half of 2026 to provide early access to the PRECISE-SG100K resource of 100,000 participants dataset. This 2^nd Call for Proposals is open only to Singapore public academic and clinical researchers.

Please check the PRECISE website and newsletters regularly for updates on the 2^nd Call for Proposals. Until then, PRECISE-SG100K is not actively accepting new research proposals.
Requests from strategic national programmes: PRECISE-SG100K recognises that research proposals and data access requests from strategic national programmes will arise periodically. We welcome these requests for review.

Please direct enquiries to research@precise.cris.sg.
Requests involving overseas collaborators or industry partners: During the early access period (2024 – 2026), research proposals and data access requests involving overseas collaborators or industry partners are reviewed by PRECISE-SG100K on a case-by-case basis, with the expectation that the overseas collaborator or industry partner must demonstrate return of tangible benefits to Singapore.

Please direct enquiries to research@precise.cris.sg.