Instead of treating all patients the same way, precision medicine takes individual variations in genetics, environmental and lifestyle factors into account, allowing doctors to more accurately predict which treatment and prevention strategies will work in different groups of people. Enabled by tools to analyse data on a large scale and with DNA sequencing becoming more affordable, precision medicine can improve healthcare by giving doctors a more detailed understanding of each patient.
With several different subtypes, causes and therapies, diagnosing and managing diabetes have become a complicated problem. Precision medicine could hold the answer. Diabetes is a serious issue in Singapore, where 400,000 people suffer from the chronic disease. By 2030, however, that number is set to increase by 50 percent to 600,0001, driven by changing […]
Armed with cutting-edge technologies, scientists have assembled the first-ever gapless sequence of the entire human genome, providing new DNA puzzle pieces for precision medicine to probe. After more than a decade of research and nearly US$3 billion dollars, scientists triumphantly announced the sequencing of the human genome in 2003. Since then, the landmark Human Genome […]
Other pieces of the Precision Medicine puzzle Besides your genes, what else affects your health? Here, we guide you through ‘omics approaches for investigating disease and advancing precision medicine. Previously, we saw how your DNA can impact health and disease. As important as it is, genomics alone won’t capture the full picture of all the […]
It may be commonly inherited and potentially life-threatening, but familial hypercholesterolemia remains an underdiagnosed and undertreated condition. Precision medicine could change that. Mei Yen was just 21 when she started getting occasional chest pains. At the time, she still thought of cardiovascular disease as an affliction that only pertained to the old and overweight. Nevertheless, […]
Laying the Scientific Groundwork A robust data-sharing framework based on sound scientific principles needs to be in place before Singapore can realise the full potential of precision medicine, says PRECISE CSO John Chambers. Almost a third of all deaths in Singapore have their roots in cardiovascular conditions such as heart disease or stroke. Given the […]
From Fruit Fly Scientist to Founder of a Biotech Start-up Spurred by his desire to impact human health, Professor Liu Jianjun reflects on his career in precision medicine, which has recently been recognised with the 2020 President’s Science Award. The fields of genetics and genomics have exploded since the landmark Human Genome Project began […]
Precision medicine promises to revolutionise the way healthcare is delivered, transforming it from a one-size-fits-all approach to something more tailored. Here are specific examples of how precision medicine is already making an impact and how it could help better predict, prevent, treat and manage health conditions for all.
A deep dive into the genomes of Singapore’s three major Asian ethnic groups holds the promise to wide-ranging implications for precision medicine across the globe. When perusing the label on a drug packet, you will likely be presented with two dose recommendations: one for adults and one for children. While you may find that […]
Making Precision Medicine Mainstream Precision medicine is already impacting patients’ lives and could help doctors do more for their patients, says PRECISE’s Chief Medical Officer, Professor Tai E Shyong. Think about the last time you visited your doctor. You probably sat down and told her about your symptoms, had a quick physical examination and—if there […]