Editorial Features
- 19 April 2023Driving Better Health Outcomes: TRUSTed Data Ecosystem
Mention precision medicine and what probably comes to mind are cutting-edge technologies such as genome sequencing and pharmacogenomics. But without safe and expedient access to good data, these technologies remain promises. “Data is key to unlocking the full potential of precision medicine,” says Ms. Koh Mingshi, Director, Chief Health Scientist Office, Ministry of Health. “To […]
Read More - 12 April 2023Driving The Next Frontier In Cancer Treatments
Cancer remains to be the leading cause of death in Singapore, accounting for over 28% of all deaths annually.[1] But the good news is, compared to when the Singapore Cancer Registry first began tracking population-based cancer in 1968, the survival rate is decidedly higher today. Professor Chng Wee Joo, Executive Director, Singapore Translational Cancer Consortium […]
Read More - 05 April 2023No Child’s Play In Paediatric Precision Medicine
While precision medicine is more frequently associated with adult diseases, it clearly has a role to play in paediatrics. Dr. Saumya Shekhar Jamuar who holds concurrent appointments as Senior Consultant, KK Women’s and Children’s Hospital (KKH), and Deputy Director (Clinical), SingHealth Duke-NUS Institute of Precision Medicine cannot agree more. Dr. Jamuar plays an active role […]
Read More - 29 March 2023Genetic Counselling: Job, Passion, and Calling
Yasmin Bylstra, Senior Principal Genetic Counsellor, SingHealth Duke-NUS Institute of Precision Medicine (PRISM), appreciates the opportunity to journey alongside patients through different stages of life. “As genetic counsellors, we take the time to understand our patients and their circumstances during appointments. We sit down with them to go through their genetic information and address […]
Read More - 22 March 2023Diving Into The Clinical Side Of Genetic Counselling
To Breana Cham, Senior Principal Genetic Counsellor, KK Women’s and Children’s Hospital (KKH), life and death situations about genetic conditions are common topics on the job. Through consultations, genetic counsellors like Breana help patients and families understand the medical, psychological and hereditary significance of genetic conditions—and how to manage them. “‘If you or your […]
Read More - 17 March 2023Working the Nuts and Bolts in a Cohort Study
The recent rollout of SG100K offers the potential to learn factors associated with health and diseases that Singaporeans—and possibly half the world’s population—are predisposed to. More excitingly, this knowledge promises to shape the precision medicine landscape. Associate Professor Sim Xueling from the National University of Singapore, Saw Swee Hock School of Public Health shares insights […]
Read More - 08 March 2023Growing Precision Med’s Role in Paediatrics and Beyond
In celebration of International Women’s Day, meet women who are advancing precision medicine in Singapore. This is Part One of our four-part series celebrating the achievements of women in STEM.
Read More - 22 February 2023Exploring RNA’s Diverse Structural Landscape
With high throughput technologies, Yue Wan looks to address big-picture questions in cell biology by probing RNA molecular structures. A molecule’s structure can tell a lot about its purpose. Proteins with pockets might catalyse reactions, while those with cavities might transport ions. Like proteins, strands of ribonucleic acids (RNA) can also gain new functions […]
Read More - 15 February 2023Rewriting The Human Genome
By using emerging gene editing techniques to modify and engineer DNA, Dr Chew Wei Leong and his team at the Genome Institute of Singapore are imagining a world without disease. Dr Chew Wei Leong, Group Leader and Associate Director at A*STAR’s Genome Institute of Singapore (GIS), has one goal: to rewrite the human genome. It […]
Read More - 08 February 2023Putting Genomic Data To Good Use
Assistant Professor Adrian Teo and his colleagues at the National University of Singapore’s Yong Loo Lin School of Medicine believe in the power of localised translation research in support of Singapore’s precision medicine agenda. In April 2022, nine-month-old Teddi Shaw was diagnosed with a rare and deadly metabolic disorder: metachromatic leukodystrophy, or MLD. Caused by […]
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